The Estimating the Size of Populations through a Household Survey (EPSHS), sought to assess the feasibility of the network scale-up and proxy respondent methods for estimating the sizes of key populations at higher risk of HIV infection and to compare the results to other estimates of the population sizes. The study was undertaken based on the assumption that if these methods proved to be feasible with a reasonable amount of data collection for making adjustments, countries would be able to add this module to their standard household survey to produce size estimates for their key populations at higher risk of HIV infection. This would facilitate better programmatic responses for prevention and caring for people living with HIV and would improve the understanding of how HIV is being transmitted in the country. The specific objectives of the ESPHS were: 1. To assess the feasibility of the network scale-up method for estimating the sizes of key populations at higher risk of HIV infection in a Sub-Saharan African context; 2. To assess the feasibility of the proxy respondent method for estimating the sizes of key populations at higher risk of HIV infection in a Sub-Saharan African context; 3. To estimate the population size of MSM, FSW, IDU, and clients of sex workers in Rwanda at a national level; 4. To compare the estimates of the sizes of key populations at higher risk for HIV produced by the network scale-up and proxy respondent methods with estimates produced using other methods; and 5. To collect data to be used in scientific publications comparing the use of the network scale-up method in different national and cultural environments.