The 2016 SLMIS, a comprehensive, nationally-representative household survey, was designed in line with the Roll Back Malaria Monitoring and Evaluation Working Group (RBM-MERG) guidelines. The primary objective of the survey was to provide up-to-date estimates of basic demographic and health indicators related to malaria. On site in Sierra Leone, the survey team collected data on vector control interventions such as mosquito nets and indoor residual spraying of insecticides, on intermittent preventive treatment of malaria in pregnant women, and on care seeking and treatment of fever in children. Young children were also tested for anaemia and for malaria infection. Knowledge of malaria was assessed among interviewed women. The information collected during the survey will assist policy makers and programme managers in evaluating and designing programmes and strategies for improving malaria control. The broader goal is to improve the health of the country’s population and provide estimates of indicators defined in the 2016-2020 National Malaria Strategic Plan (MoHS 2015a).